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Key words: sealability, pharmaceutical vacuum packaging, gas residue, vacuum packaging residual oxygen meter, RGT-01
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It is well known that the main cause of mold spoilage is caused by the activity of microorganisms, and the microorganisms on the surface of the drug are generally propagated under aerobic conditions. Vacuum packaging of drugs uses this principle to remove oxygen from the inside of the package and the cells of the drug. To make the microbes lose the "environment of survival" and completely isolate the contents from the external environment, so as to maintain the original nature of the drug and store it for a long time. It can be seen that the overall sealing performance of the vacuum packaging of the drug and the internal gas residual amount directly affect the storage life of the drug and the change of the original property, which is an indicator that the relevant enterprises must pay attention to and control. Labthink will then briefly introduce the sealing performance and gas residue detection of vacuum packaging of pharmaceutical products with RGT-01 vacuum packaging residual oxygen meter.
Sealing performance refers to the reliability of vacuum packaging seals. This test ensures the integrity of the entire product packaging seal. The principle of vacuum packaging determines the importance of its overall sealing and internal gas residuals. The commonly used methods for sealing performance testing are as follows: * Use a leak tester, using the vacuum principle, and keep at -30kpa, -50kpa, -70kpa, -90kpa for 0.5 minutes according to national standards, mainly for vacuum packaging. Recovery of the sample after the test. Of course, the above method is based on the principle of visual inspection and is a qualitative test method. The second is to seal the performance test equipment by the principle of positive pressure method. The gas is injected into the package to monitor the change of pressure to determine its sealing performance. This method is obviously a quantitative test method, but it is destructive to the sample. The test has certain limitations for vacuum packaging testing. Labthink's new RGT-01 vacuum packaging residual oxygen meter solves the problems of the above two principles of equipment testing vacuum packaging; RGT-01 vacuum packaging residual oxygen meter uses differential pressure test principle and liquid level Analyze the combined testing technology. In the test, first fill the vacuum chamber with water, cover the sealing plate, and then slowly inject water into the designated area in the metering cylinder, cover the upper cover, press the sealing plate, and test the test. The cavity is evacuated until the sample expands. After the Zui, the liquid level analysis and related calculations are used to obtain the amount of residual gas in the package. At the same time, the sealing performance of vacuum packaging and packaging containers of various drugs can be accurately and quantitatively measured.
The RGT-01 vacuum packaging residual oxygen meter adopts the embedded computer system platform, which has high test precision and convenient operation. The system will display the test information such as pressure value and curve in real time during the test process. At the same time, the database storage technology is used to save the detailed information of each test. And provide convenient and diversified query function, the user can view the historical test data by curve or data list; the system also supports the test result comparison, the user sets the standard value and error range before the test starts, and the system automatically judges after the test is completed. Whether the test results are within the standard error range, and intuitively inform the user whether the sample is qualified; in addition, the RGT-01 vacuum packaging residual oxygen meter also has a calibration data recovery function, which effectively solves the adverse effects caused by misoperation. The safety of the system is guaranteed to a large extent; the system can repair key information data in a manner specified by the user, such as the calibration data recovery operation of each sensor. In addition, the instrument also has multi-level authority management functions for users. It can effectively control the degree of control of different instruments by different users, and effectively eliminate the use of unauthorized use and illegal use. It also supports bilingual Chinese and English, convenient for Chinese users and English. User use.
Of course, after ensuring the sealing performance and gas residual capacity of the vacuum packaging of the drug, it is necessary to control other indicators such as barrier properties, heat sealing strength, friction coefficient, peel strength, etc., to ensure the quality of the product during the shelf life. For more information about the relevant testing instruments, you can visit the company to view specific information. Jinan Languang Electromechanical Technology Co., Ltd. is willing to enhance exchanges and cooperation with enterprises and institutions in the industry.
Solution on the sealing performance of pharmaceutical vacuum packaging
Abstract: The overall sealing performance and internal gas residue of pharmaceutical vacuum packaging directly affect the storage life and changes of original properties of pharmaceuticals, which is an indicator that relevant enterprises must pay attention to and control.