How to choose the right laboratory spray dryer

Spray drying is a drying method for rapidly drying liquid materials. After the liquid material is atomized in the drying chamber, the moisture is instantaneously vaporized in contact with hot air to obtain a dried product, which can directly make the solution and the milk. The turbid liquid is dried into a powdery or granular product, and the processes of evaporation, concentration, pulverization, etc. can be omitted, and the obtained particles are uniformly distributed.

Spray drying has the characteristics of fast heat transfer, rapid evaporation of water, instant drying time, good product quality, good solubility, and can improve the dissolution rate of some preparations. In addition, spray drying can also be used to prepare microcapsules.

“Workers must first sharpen their tools if they want to do their job well”. Researchers may need laboratory sprays of different types for the physical or chemical properties of different materials, as well as the size and solubility of the powder or particles that need to be obtained in the experiment. The dryer can get the best experimental results.

1) High sugar content (if juice, Chinese herbal medicine or natural product extract) or heat sensitive material (such as enzyme preparation, etc.)

Because most of the polysaccharide disaccharides have a relatively low melting point, the sugar melts when heated, and the polysaccharide disaccharide itself is relatively easy to absorb moisture, so ordinary spray dryers are prone to sticking, which is not easy. Get good dry powder or granules. In addition, like enzyme preparations, live bacteria and some high-molecular materials that are easily denatured at high temperatures, ordinary spray dryers are used, and the materials are easily deactivated or denatured. At this time, the inlet air temperature and air output of the spray dryer are lowered. Temperature, you can get better experimental results, Shanghai Yach Instrument Equipment Co., Ltd. () YC-1000 laboratory spray dryer and YC-2000 laboratory low temperature spray dryer can be relatively low The wind temperature is tested. For example, the inlet air temperature of the YC-1000 laboratory spray dryer can be set to 110. Generally, the high sugar content of the material can obtain better particles. Some materials may have a lower melting point of sugar, while the YC-2000 laboratory low-temperature spray dryer combines the advantages of spray drying and vacuum drying. At 60-80 inlet air temperature, the spray drying process can be completed. The enzyme preparation, the living bacteria, and the like are instantaneously dried at such a low temperature, and the activity is not affected at all.

2) The solvent is an organic solvent or an easily oxidizable material.

In spray drying, it is difficult to dry the organic solvent. Generally, the organic solvent will be inflammable and explosive. The explosion-proof closed laboratory spray dryer can circulate the material in a closed drying system. The whole system is filled with inert gas. (such as nitrogen or argon), can avoid the contact of organic solvent gas with external oxygen, ensuring safe production. Shanghai Yacheng YC-015A experimental organic solvent spray dryer adopts a safe nitrogen (or other inert gas) closed circulation mode. The whole system is closed, and the oxygen concentration is monitored online. Once the oxygen concentration in the system reaches 2%. The system will automatically stop the machine and alarm. It is a small-scale spray dryer for laboratory organic solvents with good safety and easy operation. It can be used for flammable and toxic solvents through the closed loop of nitrogen and the complete recovery of solvent. It is processed and dried with oxidizable substances. Further, since the boiling point of the organic solvent is low, it is possible to dry the substance which is susceptible to heat denaturation by a low-temperature drying method.

3) Materials that require large particle powder

In some experiments, researchers hope to get some samples of large particles, such as the catalyst industry, generally need about 100 microns of particles to have better catalytic effect, but ordinary spray dryer can only get particles below 30 microns. , Shanghai Yacheng YC-1000 laboratory spray drying granulator, can be better to achieve the purpose of the experiment. YC-1000 spray granulator can be used as a separate spray dryer to obtain particles of about 100 microns, and can also achieve granulation of small particles, and can obtain large particles of 100 microns or more.

4) Materials with extremely poor heat sensitivity or improved solubility

Some materials are basically not heated, the traditional freeze-drying time is very long, and the dried materials are in a block shape, the fluidity is poor, and the solubility is not very good. Compared with the traditional freeze-drying technology, Shanghai Yacheng YC-3000 laboratory spray freeze dryer has the following advantages: (1) The atomized and dispersed fine droplets are immersed in low temperature to freeze rapidly, which can weaken the growth of ice crystals and reduce ice crystals. Destruction of liposomes, avoiding leakage and burst release of materials such as drugs; (2) Forming spherical particles with microporous structure after vacuum drying, the fluidity is good, and the size of the particles can be changed by changing the spraying process. adjust. YC-3000 laboratory spray freeze dryer is suitable for low temperature drying of heat sensitive, viscous, active materials and materials with high sugar content, such as Chinese herbal medicine natural product extract, dairy products, biological preparations, enzyme preparations, fruit juice , polymer materials, etc.

For materials that require direct access to nanomaterials, the YC-3000 laboratory spray freeze dryer is also an excellent choice.

5) Conventional materials

Some laboratories are used for the preparation of conventional powders or for drying materials. You can use Shanghai Yacheng YC-015 Laboratory Spray Dryer. YC-015 is small in size, fast in speed, low in noise, easy to operate, and can be completed in 20ML. In one experiment, the dried powder has a good sphericity and the particle size is too distributed. In particular, the machine has a spray head water cooling device and a tower wall purging function, which greatly expands the application of the laboratory spray dryer. For some special materials containing chloride ions, Shanghai Yacheng uses a special type of stainless steel resistant to chloride ion to meet the actual needs of special industries.